Clinical evidence
Curated variant–drug–disease evidence and clinical assertions with evidence levels, AMP/ASCO/CAP tiers and citations.
Source: CIViC
Precision oncology · Live public evidence
Every piece of public cancer evidence, in one private workspace.
Oncotics brings live clinical evidence, clinical trials, FDA drug and device records, gene and protein biology, and literature together for any gene, variant, drug, device, diagnostic, disease or trial — without ever storing what you search.
- Free · no sign-up
- No cookies or tracking
- Searches never stored
- 19 live public sources
- Every fact shows its source
What Oncotics does
What is Oncotics?
Oncotics is a free, privacy-first precision oncology workspace. Type a gene, variant, drug, device, diagnostic, disease or trial ID and Oncotics works out what it is, asks the right public databases directly from your browser, and connects the answers: curated evidence, trials, FDA labels, approvals, safety signals, device clearances and approvals, companion diagnostics, protein biology and papers. Each result carries its source, retrieval time and a link to the official record.
Clinical trials
Search by gene, variant, drug, device or condition; filter by status, phase, age and location; read full study details.
Source: ClinicalTrials.gov
Drug intelligence
FDA labels, Drugs@FDA approval history, FAERS adverse-event summaries, enforcement reports, RxNorm names and chemistry.
Sources: openFDA, RxNorm, ChEMBL, PubChem
Devices & diagnostics
510(k), De Novo and PMA records, classification, UDI, MAUDE events, recalls and companion-diagnostic links — with clearance and approval kept distinct.
Source: openFDA device endpoints (may lag official FDA databases)
Biology
Gene and variant annotation, variant effect prediction, protein function, pathways, interactions, structures, cancer mutation frequency, target validation and GWAS.
Sources: Ensembl, MyGene, MyVariant, UniProt, Reactome, STRING, AlphaFold, Open Targets, cBioPortal, GWAS Catalog
Literature
Relevant papers with abstracts, open-access links and citation counts, filterable by year, reviews and open access.
Source: Europe PMC
Who benefits
Who benefits from Oncotics, and how?
Anyone who needs a fast, sourced overview of public precision oncology evidence — without jumping between a dozen websites or handing over their search history.
| Who | How Oncotics helps |
|---|---|
| Cancer researchers | See evidence, trials, biology and papers for a gene or variant on one screen, with sources to cite. |
| Clinicians (for qualified review) | Gather the published evidence, labels and open trials behind a biomarker before discussing it with colleagues — never as a treatment decision. |
| Bioinformaticians | Check variant consequences across Ensembl VEP and MyVariant, with transcript-level detail and conflicts shown side by side. |
| Oncology pharmacists | Review FDA label sections, approval history, adverse-event summaries and recalls for a drug in minutes. |
| Clinical trial navigators | Filter trials by biomarker, status, phase, age and location, and open full study records. |
| Regulatory affairs & laboratory medicine | Look up 510(k), De Novo and PMA records, product codes, UDI, MAUDE and recalls, and possible companion-diagnostic links. |
| Students & educators | Learn how genes, variants, drugs, trials and diagnostics connect, using real public data. |
How it works
How does Oncotics work?
Type anything
A gene, variant, rsID, HGVS, drug or brand, disease, trial ID, PMID, device number, product code or UDI-DI.
Oncotics identifies it
It recognises the query type, shows its confidence, and lets you correct it. It never guesses silently.
Your browser asks the sources
A small set of live public sources is queried first, directly from your browser. Deeper sources load when you open them.
Explore connected evidence
Move from gene to variant to evidence, therapy, trial, FDA record, device and paper. Compare, pin and export — all in memory.
When to use it
When is Oncotics useful?
- Starting a literature review or grant background on a gene or biomarker.
- Checking which trials mention a variant such as KRAS G12C, and which are recruiting.
- Reviewing a drug’s current FDA label, approvals and reported adverse events.
- Confirming whether a diagnostic is FDA-cleared (510(k)), De Novo, or approved (PMA).
- Looking up an rsID or HGVS notation and its predicted consequence.
- Teaching precision oncology with real, sourced examples.
Why Oncotics
Why was Oncotics built?
Precision oncology evidence is spread across many public databases, each with its own search, identifiers and caveats. Oncotics connects them in one place while staying honest: live data is labeled live, links are labeled links, fuzzy matches are never shown as exact, and every record points back to its official source.
It is private because health-related searches are sensitive. There is no server to collect them.
Where
Where does the data come from, and where does Oncotics run?
Oncotics runs in your web browser on any device — desktop, tablet or phone — at oncotics.com/precision-oncology-workspace/. The data comes directly from these public providers:
CIViC (opens in a new tab)
curated clinical evidence for cancer variants
ClinicalTrials.gov (opens in a new tab)
registered clinical studies (U.S. National Library of Medicine)
openFDA (opens in a new tab)
FDA drug labels, approvals, adverse events, recalls, and device 510(k), De Novo, PMA, classification, UDI, MAUDE and recall records
RxNorm (opens in a new tab)
drug name normalization
Ensembl (opens in a new tab)
genome annotation and variant effect prediction (VEP)
MyGene.info and MyVariant.info (opens in a new tab)
aggregated gene and variant annotation, including ClinVar and dbSNP fields
UniProt (opens in a new tab)
protein function, domains and structures
Reactome, STRING and AlphaFold DB (opens in a new tab)
pathways, protein interactions and predicted structures
Open Targets and cBioPortal (opens in a new tab)
target–disease associations and cancer cohort mutation frequencies
GWAS Catalog, ChEMBL, PubChem and EBI OLS (opens in a new tab)
variant–trait associations, compound data and ontologies
Europe PMC (opens in a new tab)
biomedical literature, abstracts and open-access links
Privacy by design
What happens to my searches?
- No account, cookies, browser storage, analytics or tracking pixels.
- No Oncotics server: requests go straight from your browser to the provider.
- Nothing is saved; refresh or Clear Session wipes everything.
- Exports are created on your device and never uploaded.
- Inputs that look like patient information are rejected.
What Oncotics is not
Responsible by default
Educational and research use only. Oncotics does not diagnose, recommend treatments or dosing, determine trial eligibility, or give regulatory or procurement advice.
Computational predictions are not diagnoses, adverse-event reports do not prove causality, and openFDA device records may lag official FDA databases.
FAQ
Frequently asked questions
What is Oncotics?
Oncotics is a free, privacy-first precision oncology research workspace at oncotics.com. You type a gene, variant, drug, device, diagnostic, disease or trial ID, and Oncotics shows live public evidence about it — clinical evidence, trials, FDA drug and device records, biology and literature — in one place, with the source of every fact.
Who is Oncotics for?
Cancer researchers, clinicians preparing for qualified review, bioinformaticians, oncology pharmacists, clinical trial navigators, regulatory affairs and laboratory medicine teams, biomedical students and anyone learning precision oncology.
Is Oncotics free? Do I need an account?
Yes, it is free, and no account is needed. Open the Precision Oncology Workspace and start searching.
Does Oncotics store my searches?
No. Oncotics has no backend, database, cookies, browser storage or analytics. Your browser sends each request directly to the public data provider, and everything is cleared when you refresh the page or press Clear Session. Each provider may log requests under its own policy.
Where does the data come from?
From public, documented sources including CIViC, ClinicalTrials.gov, openFDA, RxNorm, Ensembl, MyGene.info, MyVariant.info, UniProt, Reactome, STRING, AlphaFold DB, Open Targets, cBioPortal, the GWAS Catalog, ChEMBL, PubChem, EBI OLS and Europe PMC. Sources that cannot be queried safely from a browser are offered as clearly labeled official links.
Can Oncotics tell me which treatment or trial is right for a patient?
No. Oncotics is for education and research. It does not diagnose, recommend treatments or dosing, or decide trial eligibility. Confirm everything with current guidelines, trial sponsors, regulators and qualified clinicians.
What is the difference between FDA clearance and FDA approval for devices?
A 510(k) is a clearance based on substantial equivalence, and a De Novo is a classification for novel lower-risk devices. A PMA is an approval for higher-risk devices. Oncotics labels each record with its correct pathway and never calls a 510(k) “approved”.
Can I search for companion diagnostics?
Yes. Open a targeted therapy and choose “Find companion diagnostics”. Oncotics shows statements from the drug label and device records that name the drug, each with a confidence label, next to the FDA’s official companion-diagnostics list, which remains the authoritative source.
What kinds of queries does it understand?
Gene symbols (EGFR), variants (BRAF V600E), rsIDs (rs113488022), HGVS (NM_004333.6:c.1799T>A), drugs and brands (osimertinib, Tagrisso), diseases (melanoma), trial IDs (NCT02296125), PMIDs, DOIs, UniProt and Ensembl IDs, 510(k), De Novo and PMA numbers, FDA product codes, regulation numbers and UDI-DIs.
Should I enter patient information?
No. Do not enter names, dates of birth, record numbers, device serial or lot numbers tied to a patient, genomic files or clinical notes. The workspace rejects inputs that look like personal health information.
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